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Cell shapes decode molecular phenotypes in image-based spatial proteomics
Cell morphology, learned from image-based spatial proteomics, is shown to predict molecular phenotypes — bridging single-cell imaging and proteomics.
Trang Le
,
William D. Leineweber
,
Matheus P. Viana
,
Anthony J. Cesnik
,
Jan N. Hansen
,
Wei Ouyang
,
Susanne M. Rafelski
,
Emma Lundberg
PDF
DOI
Roadmap on deep learning for microscopy
A collaborative community roadmap surveying how deep learning is applied across microscopy — image restoration, detection, segmentation, classification, tracking, and multimodal fusion — with its possibilities and limitations.
Giovanni Volpe
,
Carolina Wählby
,
Lei Tian
,
Wei Ouyang
PDF
DOI
Image based subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing
Large-scale immunofluorescence profiling maps how SARS-CoV-2 reshuffles the host protein landscape across 602 proteins, then screens approved drugs against the changed targets — yielding a 100,000-image public resource and pinpointing elesclomol as an antiviral modulator.
Marianna Tampere
,
Trang H. Le
,
Elin Asp
,
Adelinn Kalman
,
Jayasankar Mohanakrishnan Kaimal
,
Duncan Njenda
,
Anna Backstrom
,
Ulrika Axelsson
,
Hao Xu
,
Wei Ouyang
,
Hanna Axelsson
,
Francesco Marabita
,
Elisabeth Moussaud-Lamodiere
,
Carolina Oses Sepulveda
,
Brinton Seashore-Ludlow
,
Caroline Vernersson
,
Ali Mirazimi
,
Emma Lundberg
,
Päivi Östling
,
Charlotte Stadler
PDF
DOI
U-FISH: a fluorescent spot detector for imaging-based spatial-omics analysis
A universal deep-learning approach for accurate FISH spot detection across imaging-based spatial-omics datasets.
Weize Xu
,
Huaiyuan Cai
,
Qian Zhang
,
Zhengze Wang
,
Jiajun Yang
,
Xiaofeng Wu
,
Chengwen Li
,
Chenghua Cui
,
Changzhi Liu
,
He Jin
,
Florian Mueller
,
Jinxia Dai
,
Hao Chen
,
Wei Ouyang
,
Gang Cao
PDF
DOI
DL4MicEverywhere: deep learning for microscopy made flexible, shareable and reproducible
A framework that makes deep-learning pipelines for microscopy flexible, shareable, and reproducible across computing environments.
Ivan Hidalgo-Cenalmor
,
Joanna W. Pylvanainen
,
Mariana G. Ferreira
,
Craig T. Russell
,
Alon Saguy
,
Ignacio Arganda-Carreras
,
Yoav Shechtman
,
Arrate Munoz-Barrutia
,
Beatriz Serrano-Solano
,
Caterina Fuster-Barceló
,
Constantin Pape
,
Emma Lundberg
,
Florian Jug
,
Joran Deschamps
,
Matthew Hartley
,
Mehdi Seifi
,
Teresa Zulueta-Coarasa
,
Vera Galinova
,
Wei Ouyang
,
Guillaume Jacquemet
,
Ricardo Henriques
,
Estibaliz Gomez de Mariscal
PDF
DOI
Macromolecular Condensation Organizes Nucleolar Sub-Phases to Set Up a pH Gradient
Matthew R King
,
Kiersten M Ruff
,
Andrew Z Lin
,
Avnika Pant
,
Mina Farag
,
Jared Lalmansingh
,
Tingting Wu
,
Wei Ouyang
,
Martin J Fossat
,
Matthew D Lew
,
others
PDF
Cite
DOI
BioImage. IO Chatbot: A Personalized Assistant for BioImage Analysis Augmented by Community Knowledge Base
Wanlu Lei
,
Caterina Fuster-Barceló
,
Arrate Munoz-Barrutia
,
Wei Ouyang
PDF
Cite
Building the next generation of virtual cells to understand cellular biology
Graham T Johnson
,
Eran Agmon
,
Matthew Akamatsu
,
Emma Lundberg
,
Blair Lyons
,
Wei Ouyang
,
Omar A Quintero-Carmona
,
Megan Riel-Mehan
,
Susanne Rafelski
,
Rick Horwitz
PDF
Cite
DOI
JDLL: A library to run Deep Learning models on Java bioimage informatics platforms
Carlos Garcia Lopez de Haro
,
Stephane Dallongeville
,
Thomas Musset
,
Estibaliz Gomez de Mariscal
,
Daniel Sage
,
Wei Ouyang
,
Arrate Munoz-Barrutia
,
Jean-Yves Tinevez
,
Jean-Christophe Olivo-Marin
PDF
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DOI
Moving beyond the desktop: prospects for practical bioimage analysis via the web
Wei Ouyang
,
Kevin W Eliceiri
,
Beth A Cimini
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DOI
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